Controlled radiofrequency ablation / RFA

RFA - Radiofrequency Ablation is an advanced endoscopic technique for treating diseased mucosa, based on the controlled delivery of radiofrequency energy to the target area. In the context of Barretts esophagus, the goal of the treatment is the selective ablation of mucosa that has undergone precancerous changes, while preserving the healthy surrounding tissues.

The procedure is performed during endoscopy, without external incisions, and enables:

• Precise and uniform ablation of the diseased mucosa
• Reduction of the risk of progression to high-grade dysplasia or esophageal cancer
• Healing and long-term replacement of the diseased mucosa with healthy mucosa

RFA is performed at a controlled depth, so that injury is limited to the mucosal layer only, which reduces the risk of scarring or esophageal stricture. Multiple treatment sessions may sometimes be required, depending on the extent of the mucosal changes.

RFA is currently considered the leading standard of care for Barretts esophagus with dysplasia, and significantly improves prognosis and long-term safety for patients.