Z-POEM adapts the POEM tunneling technique to Zenker's diverticulum. A submucosal tunnel provides access to the cricopharyngeal muscle and permits controlled division of the septum.
Why is it important? The aim is to improve emptying of the pouch and relieve swallowing difficulty, regurgitation and cough related to retained food.
Diagnosis and treatment Evaluation commonly includes a barium swallow and endoscopic assessment. Suitability depends on pouch size, anatomy, symptom burden and the patient's overall condition.
Zenker's Diverticulum is a pouch that forms at the junction between the pharynx and the upper esophagus. This condition causes food accumulation, bad breath, dysphagia, and regurgitation. The most advanced treatment today is the endoscopic division of the septum (Z-POEM) with no need for external neck incisions.
Submucosal Tunneling is an advanced endoscopic technique in which a controlled passage (tunnel) is created in the submucosal layer of the esophagus, between the mucosa and the muscle layer. This approach enables access to the muscle layer to perform a precise myotomy, without injuring the mucosa or making external incisions or opening the chest cavity.
The technique is performed under full direct visualization, with precise control of the direction, depth, and length of the tunnel, and allows:
Submucosal Tunneling forms the foundation for the Third Space Endoscopy technique and requires advanced endoscopic skill, significant experience, and in-depth knowledge of the anatomy of the esophageal wall.